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Guotai Junan's annual strategy for innovative drugs in 2025: innovative pharmaceutical companies have accelerated into the harvest period, and the valuation has been at a historical low in the past five years. Guotai Junan said that the centralized purchasing policy has become stable, mature and normalized, and the marginal impact has weakened. Innovative drugs have gained policy inclination in the medical insurance negotiation. In the past two years, the policy has continued to promote pharmaceutical innovation, and the top-level design and local supporting chain support the development of innovative drugs. Commercial insurance is expected to bring new growth momentum to China's pharmaceutical market, and the overall industry trend is upward. At present, the trend of innovative drug industry is improving, the supply continues to accelerate, and a number of domestic innovative drugs are approved soon, which is expected to drive a new round of heavy volume. At the same time, the commercialization has achieved remarkable results and has occupied a dominant position in some sub-sectors. Pharma's performance continued to differentiate, and innovative drugs and just-needed drugs performed well. Biotech commercialization continues to increase, per capita yield continues to increase, the node of turning losses is approaching, and innovation ushers in the harvest period. Horizontal comparison: compared with overseas peers, the overall valuation of domestic innovative pharmaceutical companies is in a historically low range; Vertical comparison: the valuation of SW- pharmaceutical biology and SW- chemical preparations is at a historical low in the past five years, and it is expected that the valuation of subsequent sectors will pick up.Shenzhen Holdings: Auditor replacement: PricewaterhouseCoopers resigned and Ernst & Young took over. On December 10th, Shenzhen Holdings (00604.HK) announced that according to Rule 13.51(4) of the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited, PricewaterhouseCoopers agreed to resign as the auditor of Shenzhen Holdings with effect from December 10th, 2024. At the same time, the board of directors of Shenzhen Holdings decided to appoint Ernst & Young as the new auditor of the company, which will also take effect from December 10, 2024 until the end of the next annual general meeting.China Huaneng and Huawei signed a strategic cooperation agreement. On December 6th, China Huaneng Group Co., Ltd. (hereinafter referred to as "Huaneng") and Huawei Technologies Co., Ltd. (hereinafter referred to as "Huawei") signed a strategic cooperation agreement. Wen Shugang, Chairman and Party Secretary of Huaneng Group, held talks and witnessed the signing of the contract with Meng Wanzhou, rotating chairman and CFO of Huawei, and jointly unveiled Huaneng-Huawei New Energy joint innovation lab. According to the agreement, the two sides will continue to deepen strategic cooperation in the fields of clean energy cooperation, digital transformation cooperation, the establishment of joint innovation lab, and corporate culture exchange.

A new generation of quantum chips has achieved a breakthrough in error correction capability. According to a paper published in Nature magazine on the 10th, Google's latest generation of quantum chips has achieved a breakthrough in error correction capability, that is, the error is suppressed below a critical threshold. This quantum error correction function is considered as a necessary condition to realize the practical application of quantum computing in the future. After the performance of the chip is expanded, it may be able to promote the operation requirements of large-scale fault-tolerant quantum computing.Australia's S&P/ASX200 index opened down 12.60 points, or 0.15%, at 8380.4 points on Wednesday, December 11th.During the year, there were 461 new indices, and the index investment fever continued to climb. On December 10th, in order to meet the investment demand of diversified indices, CSI Index Co., Ltd. officially released five new indices, including CSI 1000 Growth Index, CSI 1000 Value Index, CSI 2000 Growth Index, CSI 2000 Value Index and CSI 1000 Quality Balance Strategy Index. With the "listing" of the above five indexes, the number of newly-issued indexes reached 461 during the year, covering categories such as strategy, style, scale, industry, theme and other fixed-income indexes; Related index asset classes include stocks, fixed income, funds and futures. At the same time, the secondary market, this year, the heat of indexed investment is also high. Looking forward to the future, with the continuous vigorous growth of market demand and unabated heat, and the precise guidance and strong support from the supervisory level, the indexed investment ecology will become more and more perfect. (Securities Daily)

Galaxy Securities: The equity market rebounded, and the improved double-low strategy exceeded 9% during the year. According to china galaxy Securities, the last cycle (11.26-12.9) recorded 2.3%, 1.7% and 3.2% respectively (the benchmark for the same period was 2.7%). Since the beginning of this year, the performance of the three types of strategies has been 8.5%, 8.6% and 15.1% respectively (the benchmark for the same period is 6.6%), and the cumulative excess rate of return is 2-9%. In the last cycle, the equity market rebounded and repaired. Wandequan A rose by 4.05%, and CSI convertible bonds followed (2.68%), among which the double-low style (3.25%) rose higher, and the low-price enhancement and low-price large-market strategy slightly underperformed the benchmark, and the double-low improvement strategy continued to dominate.Goldman Sachs: I don't agree that gold can't reach $3,000 under a strong dollar. Goldman Sachs said that we don't agree with the view that the price of gold can't rise to $3,000 per ounce by the end of 2025 when the dollar remains strong for a long time. We predict that gold will reach $3,000 per ounce by the end of 2025, and the reduction of interest rate cuts by the Federal Reserve (rather than the strengthening of the US dollar) is the downside risk of this prediction.Greedy was elected as the representative word of Taiwan Province in 2024, and the voting results of Taiwan Province 2024 representative word were announced on the 10th. The word "Greedy" ranked first with 8736 votes and was elected as the representative word of this year. The word "dou" and "cheat" are ranked second and third respectively. This annual representative voting activity in Taiwan Province is sponsored by United Daily News. People from all walks of life are invited to recommend it, and then the people vote by telephone, SMS and online. A total of 57 candidate words were collected this year, and the top 10 were ranked as greed, struggle, fraud, resilience, earthquake, financing, danger, security and electricity in the order of votes. (Xinhua News Agency)